Somatic Mutation Analysis

Bioinformatics Training Platform (BTP) Module: Somatic Mutation Analysis

• Topic
  • Somatic Mutation Analysis
• Target Audience
  • Biologists
  • Non-bioinformaticians
  • Little to no programming expereience
• Prerequisites
  • None
• Key Learning Outcomes
  • Visualise mutational signatures present in a cohort using somatic single nucleotide mutation data in Variant Call Format (vcf) files.
  • Compare analysis output with published results to identify common mutational signatures.
  • Have gained overview knowledge of how somatic signatures can help with cohort cancer analysis.
  • Run the IntOGen analysis software on cohort mutation data.
  • Have gained experience of the structure of the analysis output files in order to identify potential driver genes.
  • Have gained overview knowledge of different methods for identification of genes important in cancers.
• Time Required *

License

The contents of this repository are released under the Creative Commons Attribution 3.0 Unported License. For a summary of what this means, please see: http://creativecommons.org/licenses/by/3.0/deed.en_GB