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baredSC | ||
======== | ||
[![PyPI Version](https://img.shields.io/pypi/v/baredsc.svg?style=plastic)](https://pypi.org/project/baredSC/) [![DOI](https://zenodo.org/badge/370966963.svg)](https://zenodo.org/badge/latestdoi/370966963) | ||
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[![PyPI Version](https://img.shields.io/pypi/v/baredsc.svg?style=plastic)](https://pypi.org/project/baredSC/) [![bioconda-badge](https://img.shields.io/conda/vn/bioconda/baredSC.svg?style=plastic)](https://anaconda.org/bioconda/baredsc) [![DOI](https://zenodo.org/badge/370966963.svg)](https://zenodo.org/badge/latestdoi/370966963) | ||
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baredSC (Bayesian Approach to Retreive Expression Distribution of Single Cell) is a tool that uses a Monte-Carlo Markov Chain to estimate a confidence interval on the probability density function (PDF) of expression of one or two genes from single-cell RNA-seq data. It uses the raw counts and the total number of UMI for each cell. The PDF is approximated by a number of 1d or 2d gaussians provided by the user. The likelihood is estimated using the asumption that the raw counts follow a Poisson distribution of parameter equal to the proportion of mRNA for the gene in the cell multiplied by the total number of UMI identified in this cell. | ||
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Documentation | ||
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Visit [our documentation](https://baredsc.readthedocs.io) to see the possible options and follow the tutorials. | ||
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Citation | ||
-------- | ||
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If you are using baredSC, please cite our [biorxiv paper](https://doi.org/10.1101/2021.05.26.445740). |
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--extra-index-url https://obswww.unige.ch/~delisle | ||
numpy >=1.16 | ||
matplotlib >=3.1.1 | ||
pandas >=0.25.0 | ||
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