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FiMAP (Fast Identity-by-Descent Mapping Test)

Description

FiMAP is an R package for performing efficient identity-by-descent (IBD) mapping test using IBD segments to identify genomic regions associated with complex traits in large biobank-scale cohorts.

Installing

FiMAP imports R packages CompQuadForm, foreach, parallel, Matrix, GMMAT. In addition, FiMAP requires doMC to run parallel computing. These dependencies should be installed before installing FiMAP.

For optimal computational performance, it is recommended to use an R version configured with the Intel Math Kernel Library (or other fast BLAS/LAPACK libraries). See the instructions on building R with Intel MKL.

To install FiMAP from GitHub, please use

devtools::install_github("hanchenphd/FiMAP", ref = "main")

Version

The current version is 0.1.0 (July 1, 2021).

License

This software is licensed under GPL-3.

Contact

Please refer to the R help document of FiMAP for specific questions about each function. For comments, suggestions, bug reports and questions, please contact Han Chen (Han.Chen.2 AT uth.tmc.edu). For bug reports, please include an example to reproduce the problem without having to access your confidential data.

References

If you use FiMAP, please cite

  • Chen H, Naseri A, Zhi D. (2021) FiMAP: A Fast Identity-by-Descent Mapping Test for Biobank-scale Cohorts. medRxiv 2021.06.30.21259773 [Preprint]. July 5, 2021. DOI: 10.1101/2021.06.30.21259773.
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