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If the pattern for H1 does not match, the whole sequence space shall be used to determine a match for H3. Today, if a V region is complete only on the C-terminus, antibody.py complains about the use of an undefined variable. For L1 the situation is anologous.
I found this now while working with data from immune repertoire analyses with next-generation sequencers which, for our local setup, tend to lack the N-terminal Fv region, so the pattern for H1 does not match.