Log fold change

[cansavvy]

Description

This step has now been split into two main functions! gimap_normalize() and calc_crispr() are the new stuff here.

Here is how I test this overall:

 gimap_dataset <- get_example_data("gimap") %>%
   gimap_filter() %>%
   gimap_annotate() %>%
   gimap_normalize(
     timepoints = "day",
     replicates = "rep")

Instructions for Reviewers

I have a series of TODOs in the code that ask questions -- either the Berger Lab can help us answer or @kweav if you have insights that's great too. Besides just carefully scrutinizing this and seeing if it more or less is giving the same story as the original code.

A big piece here is that it will need to be re-run once we have filtering steps ready.