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Added functionalities and saving raw table #67

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fgualdr opened this issue Jan 31, 2024 · 0 comments
Open

Added functionalities and saving raw table #67

fgualdr opened this issue Jan 31, 2024 · 0 comments

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@fgualdr
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fgualdr commented Jan 31, 2024

Hi!,

I am trying to implement crispulator to generate RAW data and test/compare CRISPR tools.
I am trying to figure out few things:

  1. how to generate experiment replicates - this often required to model L2FC by tools (i.e. DESEQ2 etc..)
  2. include ungrouped gRNA such as non-targeting gRNA which are by definition not grouped
  3. this last point might be the most trivial how to simply get/save raw read counts per gRNA per target gene per sorted bin including the "pre-sorted"?
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