diff --git a/src/curate_gpt/cli.py b/src/curate_gpt/cli.py
index 43bbbae..f66b089 100644
--- a/src/curate_gpt/cli.py
+++ b/src/curate_gpt/cli.py
@@ -5,6 +5,7 @@
 import logging
 import sys
 from pathlib import Path
+import random
 from typing import Any, Dict, List, Union
 
 import click
@@ -17,6 +18,7 @@
 from llm.cli import load_conversation
 from oaklib import get_adapter
 from pydantic import BaseModel
+from tqdm import tqdm
 
 from curate_gpt import ChromaDBAdapter, __version__
 from curate_gpt.agents.chat_agent import ChatAgent, ChatResponse
@@ -37,6 +39,8 @@
 from curate_gpt.wrappers.literature.pubmed_wrapper import PubmedWrapper
 from curate_gpt.wrappers.ontology import OntologyWrapper
 
+from oaklib.datamodels.vocabulary import IS_A, PART_OF
+
 __all__ = [
     "main",
 ]
@@ -1595,6 +1599,64 @@ def _text_lookup(obj: Dict):
     db.update_collection_metadata(collection, object_type="OntologyClass")
 
 
+@ontology.command(name="subsumption")
+@path_option
+@collection_option
+@model_option
+@click.option("--prefix", required=False, default=None, help="Prefix of terms to use, e.g. 'HP:'")
+@click.option('--predicates', multiple=True, help='Predicates of interest (e.g., is_a, part_of)')
+@click.option("--seed", required=False, default=42, help="Seed for random number generator")
+@click.option('--num_terms', required=False, default=1000, help='Number of term pairs to compare')
+@click.argument("ont")
+def subsumption_command(ont, path, collection, prefix, predicates, seed, num_terms, model, **kwargs):
+    """
+    Compare pairs of ontology terms where one subsumes the other, or one does NOT
+    subsume the other, to determine whether LLM embeddings reflect subsumption
+    relationships.
+
+    Example:
+    -------
+        curategpt subsumption  -c obo_hp $db/hp.db
+
+    """
+    if not predicates:
+        predicates = [IS_A, PART_OF]
+
+    oak_adapter = get_adapter(ont)
+    view = OntologyWrapper(oak_adapter=oak_adapter)
+    db = ChromaDBAdapter(path, **kwargs)
+    db.text_lookup = view.text_field
+
+    c = db.client.get_collection(collection)
+
+    # get all terms
+    terms = list(view.oak_adapter.all_entity_curies())
+    if prefix is not None:
+        terms = [t for t in terms if t.startswith(prefix)]
+        if not terms:
+            raise ValueError(f"No terms found with prefix {prefix}")
+
+    # choose 1000 pseudo-random terms, get ancestor info, choose a random subsuming
+    # and non-subsuming term, calculate fraction of ancestors in common while we are
+    # at it
+    random.seed(seed)
+    ancs = []
+    random_pairs = []
+    for term in tqdm(random.sample(terms, num_terms), desc="Choosing terms to compare"):
+        anc = list(view.oak_adapter.ancestors(term, predicates=predicates, reflexive=False))
+        ancs.append((term, anc))
+
+        # choose random term to pair with
+        random_other_term = random.choice(terms)
+        random_term_ancs = list(view.oak_adapter.ancestors(random_other_term,
+                                                           predicates=predicates,
+                                                           reflexive=False))
+        pair_shared_anc = len(set(anc).intersection(
+            set(random_term_ancs))) / len(anc)  # fraction of ancestors in common
+        random_pairs.append((term, random_other_term, pair_shared_anc))
+
+    pass
+
 @main.group()
 def view():
     "Virtual store/wrapper"