diff --git a/Duper/Rules/DatatypeAcyclicity.lean b/Duper/Rules/DatatypeAcyclicity.lean
new file mode 100644
index 0000000..56ce345
--- /dev/null
+++ b/Duper/Rules/DatatypeAcyclicity.lean
@@ -0,0 +1,95 @@
+import Duper.Simp
+import Duper.Util.ProofReconstruction
+
+namespace Duper
+open Std
+open RuleM
+open SimpResult
+open Lean
+open Meta
+open LitSide
+
+initialize Lean.registerTraceClass `duper.rule.datatypeAcyclicity
+
+/-- Produces a list of (possibly duplicate) constructor subterms for `e` -/
+partial def collectConstructorSubterms (e : Expr) : MetaM (Array Expr) := do
+  let isConstructor ← matchConstCtor e.getAppFn' (fun _ => pure false) (fun _ _ => pure true)
+  if isConstructor then
+    let constructorSubterms ← e.getAppArgs.mapM (fun arg => collectConstructorSubterms arg)
+    return constructorSubterms.flatten.push e
+  else
+    return #[e]
+
+/-- Returns `none` if `lit` does not compare constructor subterms, and returns `some litside` if `lit.litside`
+    is a subterm of the constructor it is being compared to. Note that `lit.litside` may not itself be a constructor
+    (e.g. `xs` is a constructor subterm of `x :: xs`) -/
+def litComparesConstructorSubterms (lit : Lit) : MetaM (Option LitSide) := do
+  let litTyIsInductive ← matchConstInduct lit.ty.getAppFn' (fun _ => pure false) (fun _ _ => pure true)
+  if litTyIsInductive then
+    trace[duper.rule.datatypeAcyclicity] "lit.ty {lit.ty} is an inductive datatype"
+    -- If `e1` is a constructor subterm of `e2`, then `e1.weight ≤ e2.weight`
+    if lit.lhs.weight < lit.rhs.weight then
+      let rhsConstructorSubterms ← collectConstructorSubterms lit.rhs
+      if rhsConstructorSubterms.contains lit.lhs then return some lhs
+      else return none
+    else if lit.rhs.weight < lit.lhs.weight then
+      let lhsConstructorSubterms ← collectConstructorSubterms lit.lhs
+      if lhsConstructorSubterms.contains lit.rhs then return some rhs
+      else return none
+    else
+      if lit.lhs == lit.rhs then return some lhs
+      else return none
+  else -- `lit.ty` is not an inductive datatype so `lit` cannot be comparing constructor subterms
+    trace[duper.rule.datatypeAcyclicity] "lit.ty {lit.ty} is not an inductive datatype"
+    return none
+
+def mkDatatypeAcyclicityProof (removedLitNum : Nat) (litSide : LitSide) (premises : List Expr)
+  (parents : List ProofParent) (transferExprs : Array Expr) (c : Clause) : MetaM Expr := do
+  Meta.forallTelescope c.toForallExpr fun xs body => do
+    let cLits := c.lits.map (fun l => l.map (fun e => e.instantiateRev xs))
+    let (parentsLits, appliedPremises, transferExprs) ← instantiatePremises parents premises xs transferExprs
+    let parentLits := parentsLits[0]!
+    let appliedPremise := appliedPremises[0]!
+    let mut proofCases : Array Expr := Array.mkEmpty parentLits.size
+    for i in [:parentLits.size] do
+      let lit := parentLits[i]!
+      if i == removedLitNum then -- `lit` is the equality asserting an acyclic constructor
+        let proofCase ← Meta.withLocalDeclD `h lit.toExpr fun h => do
+          let sizeOfInst ← mkAppOptM ``inferInstanceAs #[← mkAppOptM ``SizeOf #[lit.ty], none]
+          let litTyMVar ← mkFreshExprMVar lit.ty
+          let abstrLam ← mkLambdaFVars #[litTyMVar] $ ← mkAppOptM ``sizeOf #[some lit.ty, some sizeOfInst, some litTyMVar]
+          let sizeOfEq ← mkAppM ``congrArg #[abstrLam, h] -- Has the type `sizeOf lit.lhs = sizeOf lit.rhs`
+          let sizeOfEqFalseMVar ← mkFreshExprMVar $ ← mkAppM ``Not #[← inferType sizeOfEq] -- Has the type `¬(sizeOf lit.lhs = sizeOf lit.rhs)`
+          let sizeOfEqFalseMVarId := sizeOfEqFalseMVar.mvarId!
+          -- **TODO**: Figure out how to assign `sizeOfEqFalseMVar` an actual term (ideally generated by `simp_arith`)
+          -- The below lines attempts to use the omega procedure to generate a term for `sizeOfEqFalseMVar`, but it doesn't work
+          Elab.Tactic.Omega.omega [] sizeOfEqFalseMVarId -- Use the `omega` tactic to prove `¬(sizeOf lit.lhs = sizeOf lit.rhs)`
+          let proofCase := mkApp2 (mkConst ``False.elim [levelZero]) body $ mkApp sizeOfEqFalseMVar sizeOfEq -- Has the type `body`
+          trace[duper.rule.datatypeAcyclicity] "lit: {lit}, lit.ty: {lit.ty}, sizeOfInst: {sizeOfInst}, abstrLam: {abstrLam}, sizeOfEq: {sizeOfEq}"
+          trace[duper.rule.datatypeAcyclicity] "sizeOfEqFalseMVar: {sizeOfEqFalseMVar}, proofCase: {proofCase}"
+          Meta.mkLambdaFVars #[h] proofCase
+        proofCases := proofCases.push proofCase
+      else -- `lit` is not the equality to be removed
+        let proofCase ← Meta.withLocalDeclD `h lit.toExpr fun h => do
+          Meta.mkLambdaFVars #[h] $ ← orIntro (cLits.map Lit.toExpr) i h
+        proofCases := proofCases.push proofCase
+    let proof ← orCases (parentLits.map Lit.toExpr) proofCases
+    Meta.mkLambdaFVars xs $ mkApp proof appliedPremise
+
+/-- Implements the acyclicity rules described in section 6.4 of https://arxiv.org/pdf/1611.02908 -/
+def datatypeAcyclicity : MSimpRule := fun c => do
+  let c ← loadClause c
+  for i in [:c.lits.size] do
+    let lit := c.lits[i]!
+    match ← litComparesConstructorSubterms lit with
+    | some side =>
+      if lit.sign then -- `lit` is never true so `lit` can be removed from `c`
+        let res := c.eraseIdx i
+        let yC ← yieldClause res "datatypeAcyclicity" none -- mkDatatypeAcyclicityProof i side
+        trace[duper.rule.datatypeAcyclicity] "datatypeAcyclicity applied to {c.lits} to yield {yC.1}"
+        return some #[yC]
+      else -- `lit` is a tautology so the clause `c` can simply be removed
+        trace[duper.rule.datatypeAcyclicity] "datatypeAcyclicity applied to remove {c.lits}"
+        return some #[]
+    | none => continue
+  return none
diff --git a/Duper/Saturate.lean b/Duper/Saturate.lean
index b0bf767..cc87a7a 100644
--- a/Duper/Saturate.lean
+++ b/Duper/Saturate.lean
@@ -29,6 +29,7 @@ import Duper.Rules.NeHoist
 -- Inductive datatype rules
 import Duper.Rules.DatatypeDistinctness
 import Duper.Rules.DatatypeInjectivity
+import Duper.Rules.DatatypeAcyclicity
 -- Higher order rules
 import Duper.Rules.ArgumentCongruence
 import Duper.Rules.FluidSup
@@ -71,6 +72,7 @@ def forwardSimpRules : ProverM (Array SimpRule) := do
       identBoolFalseElim.toSimpRule,
       datatypeDistinctness.toSimpRule, -- Inductive datatype rule
       datatypeInjectivity.toSimpRule, -- Inductive datatype rule
+      datatypeAcyclicity.toSimpRule, -- Inductive datatype rule
       decElim.toSimpRule,
       (forwardDemodulation (← getDemodSidePremiseIdx)).toSimpRule,
       (forwardClauseSubsumption subsumptionTrie).toSimpRule,
@@ -95,6 +97,7 @@ def forwardSimpRules : ProverM (Array SimpRule) := do
       identBoolFalseElim.toSimpRule,
       datatypeDistinctness.toSimpRule, -- Inductive datatype rule
       datatypeInjectivity.toSimpRule, -- Inductive datatype rule
+      datatypeAcyclicity.toSimpRule, -- Inductive datatype rule
       (forwardDemodulation (← getDemodSidePremiseIdx)).toSimpRule,
       (forwardClauseSubsumption subsumptionTrie).toSimpRule,
       (forwardEqualitySubsumption subsumptionTrie).toSimpRule,