diff --git a/Cargo.lock b/Cargo.lock
index 9722fc1e6..257dba9ba 100644
--- a/Cargo.lock
+++ b/Cargo.lock
@@ -3265,6 +3265,7 @@ dependencies = [
  "tower",
  "tower-http",
  "tracing",
+ "wasmer",
 ]
 
 [[package]]
diff --git a/packages/fuel-indexer-api-server/Cargo.toml b/packages/fuel-indexer-api-server/Cargo.toml
index 6bb1cf2f1..9d1657746 100644
--- a/packages/fuel-indexer-api-server/Cargo.toml
+++ b/packages/fuel-indexer-api-server/Cargo.toml
@@ -42,6 +42,7 @@ tokio = { workspace = true, features = ["macros", "rt-multi-thread"] }
 tower = { version = "0.4", features = ["limit", "buffer"] }
 tower-http = { version = "0.3", features = ["fs", "trace", "cors", "limit"] }
 tracing = { workspace = true }
+wasmer = "4"
 
 [features]
 default = ["metrics"]
diff --git a/packages/fuel-indexer-api-server/src/api.rs b/packages/fuel-indexer-api-server/src/api.rs
index bd772bb93..05f7ecf6b 100644
--- a/packages/fuel-indexer-api-server/src/api.rs
+++ b/packages/fuel-indexer-api-server/src/api.rs
@@ -103,6 +103,11 @@ pub enum ApiError {
     SqlValidator(#[from] crate::sql::SqlValidatorError),
     #[error("ParseError: {0:?}")]
     ParseError(#[from] strum::ParseError),
+    #[error("The forc-index version {toolchain_version} does not match the fuel-indexer version {fuel_indexer_version}.")]
+    ToolchainVersionMismatch {
+        toolchain_version: String,
+        fuel_indexer_version: String,
+    },
     #[error("Other error: {0}")]
     OtherError(String),
 }
@@ -168,6 +173,9 @@ impl IntoResponse for ApiError {
                 // This is currently the only type of ParseError on the web server
                 (StatusCode::BAD_REQUEST, format!("Invalid asset type: {e}"))
             }
+            ApiError::ToolchainVersionMismatch{fuel_indexer_version, toolchain_version} => {
+                (StatusCode::METHOD_NOT_ALLOWED, format!("WASM module toolchain version `{toolchain_version}` does not match fuel-indexer version `{fuel_indexer_version}`"))
+            }
             _ => (StatusCode::INTERNAL_SERVER_ERROR, generic_details),
         };
 
diff --git a/packages/fuel-indexer-api-server/src/ffi.rs b/packages/fuel-indexer-api-server/src/ffi.rs
new file mode 100644
index 000000000..81cfff951
--- /dev/null
+++ b/packages/fuel-indexer-api-server/src/ffi.rs
@@ -0,0 +1,75 @@
+use wasmer::{
+    imports, AsStoreMut, Exports, Function, Instance, MemoryView, StoreMut, WasmPtr,
+};
+
+/// Extract the `TOOLCHAIN_VERSION` string from a WASM module. This function
+/// creates a `wasmer::Instance` in order to do this.
+pub(crate) fn check_wasm_toolchain_version(data: Vec<u8>) -> anyhow::Result<String> {
+    let mut store = wasmer::Store::default();
+
+    let module = wasmer::Module::new(&store, data.clone())?;
+
+    let mut exports = Exports::new();
+    exports.insert(
+        "ff_put_object".to_string(),
+        Function::new_typed(&mut store, |_: i64, _: i32, _: i32| {}),
+    );
+    exports.insert(
+        "ff_get_object".to_string(),
+        Function::new_typed(&mut store, |_: i64, _: i32, _: i32| 0i32),
+    );
+    exports.insert(
+        "ff_early_exit".to_string(),
+        Function::new_typed(&mut store, |_: i32| {}),
+    );
+    exports.insert(
+        "ff_put_many_to_many_record".to_string(),
+        Function::new_typed(&mut store, |_: i32, _: i32| {}),
+    );
+    exports.insert(
+        "ff_log_data".to_string(),
+        Function::new_typed(&mut store, |_: i32, _: i32, _: i32| {}),
+    );
+
+    let mut imports = imports! {};
+    wasmer::Imports::register_namespace(&mut imports, "env", exports);
+
+    let instance = wasmer::Instance::new(&mut store, &module, &imports)?;
+
+    let version = get_toolchain_version(&mut store.as_store_mut(), &instance)?;
+
+    Ok(version)
+}
+
+/// Get the toolchain version stored in the WASM module.
+pub fn get_toolchain_version(
+    store: &mut StoreMut,
+    instance: &Instance,
+) -> anyhow::Result<String> {
+    let exports = &instance.exports;
+
+    let ptr = exports
+        .get_function("get_toolchain_version_ptr")?
+        .call(store, &[])?[0]
+        .i32()
+        .ok_or_else(|| anyhow::anyhow!("get_toolchain_version_ptr".to_string()))?
+        as u32;
+
+    let len = exports
+        .get_function("get_toolchain_version_len")?
+        .call(store, &[])?[0]
+        .i32()
+        .ok_or_else(|| anyhow::anyhow!("get_toolchain_version_len".to_string()))?
+        as u32;
+
+    let memory = exports.get_memory("memory")?.view(store);
+    let version = get_string(&memory, ptr, len)?;
+
+    Ok(version)
+}
+
+/// Fetch the string at the given pointer from memory.
+fn get_string(mem: &MemoryView, ptr: u32, len: u32) -> anyhow::Result<String> {
+    let result = WasmPtr::<u8>::new(ptr).read_utf8_string(mem, len)?;
+    Ok(result)
+}
diff --git a/packages/fuel-indexer-api-server/src/lib.rs b/packages/fuel-indexer-api-server/src/lib.rs
index 9d510690c..e3ade4b2a 100644
--- a/packages/fuel-indexer-api-server/src/lib.rs
+++ b/packages/fuel-indexer-api-server/src/lib.rs
@@ -3,6 +3,7 @@
 pub mod api;
 pub mod cli;
 pub(crate) mod commands;
+pub(crate) mod ffi;
 pub(crate) mod middleware;
 pub(crate) mod models;
 pub(crate) mod sql;
diff --git a/packages/fuel-indexer-api-server/src/uses.rs b/packages/fuel-indexer-api-server/src/uses.rs
index e0f28ecf1..7b02c8a99 100644
--- a/packages/fuel-indexer-api-server/src/uses.rs
+++ b/packages/fuel-indexer-api-server/src/uses.rs
@@ -221,9 +221,20 @@ pub(crate) async fn register_indexer_assets(
 
     let multipart = multipart.ok_or_else(ApiError::default)?;
 
-    let (replace_indexer, asset_bytes) =
+    let (toolchain_version, replace_indexer, asset_bytes) =
         parse_register_indexer_multipart(multipart).await?;
 
+    let fuel_indexer_version = env!("CARGO_PKG_VERSION").to_string();
+
+    if !config.disable_toolchain_version_check
+        && toolchain_version != fuel_indexer_version
+    {
+        return Err(ApiError::ToolchainVersionMismatch {
+            toolchain_version,
+            fuel_indexer_version,
+        });
+    }
+
     queries::start_transaction(&mut conn).await?;
 
     let result = register_indexer_assets_transaction(
@@ -374,7 +385,8 @@ async fn register_indexer_assets_transaction(
 // schema, and the WASM module.
 async fn parse_register_indexer_multipart(
     mut multipart: Multipart,
-) -> ApiResult<(bool, Vec<(IndexerAssetType, Vec<u8>)>)> {
+) -> ApiResult<(String, bool, Vec<(IndexerAssetType, Vec<u8>)>)> {
+    let mut toolchain_version: String = "unknown".to_string();
     let mut replace_indexer: bool = false;
     let mut assets: Vec<(IndexerAssetType, Vec<u8>)> = vec![];
 
@@ -390,12 +402,23 @@ async fn parse_register_indexer_multipart(
             }
             name => {
                 let asset_type = IndexerAssetType::from_str(name)?;
+                if asset_type == IndexerAssetType::Wasm {
+                    toolchain_version =
+                        crate::ffi::check_wasm_toolchain_version(data.clone().into())
+                            .map_err(|e| {
+                                tracing::warn!(
+                                    "Failed to get WASM module toolchain version: {e}"
+                                );
+                                e
+                            })
+                            .unwrap_or(toolchain_version);
+                };
                 assets.push((asset_type, data.to_vec()));
             }
         };
     }
 
-    Ok((replace_indexer, assets))
+    Ok((toolchain_version, replace_indexer, assets))
 }
 
 /// Return a `Nonce` to be used for authentication.
diff --git a/packages/fuel-indexer-lib/src/config/cli.rs b/packages/fuel-indexer-lib/src/config/cli.rs
index 731e6488f..319aaa978 100644
--- a/packages/fuel-indexer-lib/src/config/cli.rs
+++ b/packages/fuel-indexer-lib/src/config/cli.rs
@@ -198,6 +198,13 @@ pub struct IndexerArgs {
         help = "Allow missing blocks or non-sequential block processing."
     )]
     pub allow_non_sequential_blocks: bool,
+
+    /// By default, Fuel Indexer will only accept WASM indexer modules compiled with the same toolchain version as the version of Fuel Indexer.
+    #[clap(
+        long,
+        help = "By default, Fuel Indexer will only accept WASM indexer modules compiled with the same toolchain version as the version of Fuel Indexer."
+    )]
+    pub disable_toolchain_version_check: bool,
 }
 
 #[derive(Debug, Parser, Clone)]
@@ -323,4 +330,10 @@ pub struct ApiServerArgs {
     /// Allow the web server to accept raw SQL queries.
     #[clap(long, help = "Allow the web server to accept raw SQL queries.")]
     pub accept_sql_queries: bool,
+    /// By default, Fuel Indexer will only accept WASM indexer modules compiled with the same toolchain version as the version of Fuel Indexer.
+    #[clap(
+        long,
+        help = "By default, Fuel Indexer will only accept WASM indexer modules compiled with the same toolchain version as the version of Fuel Indexer."
+    )]
+    pub disable_toolchain_version_check: bool,
 }
diff --git a/packages/fuel-indexer-lib/src/config/mod.rs b/packages/fuel-indexer-lib/src/config/mod.rs
index fb3cf3874..7efa28699 100644
--- a/packages/fuel-indexer-lib/src/config/mod.rs
+++ b/packages/fuel-indexer-lib/src/config/mod.rs
@@ -108,6 +108,7 @@ impl Default for IndexerArgs {
             accept_sql_queries: defaults::ACCEPT_SQL,
             block_page_size: defaults::NODE_BLOCK_PAGE_SIZE,
             allow_non_sequential_blocks: defaults::ALLOW_NON_SEQUENTIAL_BLOCKS,
+            disable_toolchain_version_check: defaults::DISABLE_TOOLCHAIN_VERSION_CHECK,
         }
     }
 }
@@ -138,6 +139,7 @@ pub struct IndexerConfig {
     pub accept_sql_queries: bool,
     pub block_page_size: usize,
     pub allow_non_sequential_blocks: bool,
+    pub disable_toolchain_version_check: bool,
 }
 
 impl Default for IndexerConfig {
@@ -160,6 +162,7 @@ impl Default for IndexerConfig {
             accept_sql_queries: defaults::ACCEPT_SQL,
             block_page_size: defaults::NODE_BLOCK_PAGE_SIZE,
             allow_non_sequential_blocks: defaults::ALLOW_NON_SEQUENTIAL_BLOCKS,
+            disable_toolchain_version_check: defaults::DISABLE_TOOLCHAIN_VERSION_CHECK,
         }
     }
 }
@@ -242,6 +245,7 @@ impl From<IndexerArgs> for IndexerConfig {
             accept_sql_queries: args.accept_sql_queries,
             block_page_size: args.block_page_size,
             allow_non_sequential_blocks: args.allow_non_sequential_blocks,
+            disable_toolchain_version_check: args.disable_toolchain_version_check,
         };
 
         config
@@ -330,6 +334,7 @@ impl From<ApiServerArgs> for IndexerConfig {
             accept_sql_queries: args.accept_sql_queries,
             block_page_size: defaults::NODE_BLOCK_PAGE_SIZE,
             allow_non_sequential_blocks: defaults::ALLOW_NON_SEQUENTIAL_BLOCKS,
+            disable_toolchain_version_check: args.disable_toolchain_version_check,
         };
 
         config
diff --git a/packages/fuel-indexer-lib/src/defaults.rs b/packages/fuel-indexer-lib/src/defaults.rs
index fa14ebef0..ad189a2de 100644
--- a/packages/fuel-indexer-lib/src/defaults.rs
+++ b/packages/fuel-indexer-lib/src/defaults.rs
@@ -137,3 +137,6 @@ pub const ACCEPT_SQL: bool = false;
 
 /// Allow missing blocks or non-sequential block processing.
 pub const ALLOW_NON_SEQUENTIAL_BLOCKS: bool = false;
+
+/// By default, Fuel Indexer will only accept WASM indexer modules compiled with the same toolchain version as the version of Fuel Indexer.
+pub const DISABLE_TOOLCHAIN_VERSION_CHECK: bool = false;
diff --git a/packages/fuel-indexer-macros/src/schema.rs b/packages/fuel-indexer-macros/src/schema.rs
index 366438e83..6192b3706 100644
--- a/packages/fuel-indexer-macros/src/schema.rs
+++ b/packages/fuel-indexer-macros/src/schema.rs
@@ -59,10 +59,14 @@ pub(crate) fn process_graphql_schema(
 
     let version_tokens = const_item("VERSION", schema.version());
 
+    let toolchain_version_tokens =
+        const_item("TOOLCHAIN_VERSION", env!("CARGO_PKG_VERSION"));
+
     let mut output = quote! {
         #namespace_tokens
         #identifer_tokens
         #version_tokens
+        #toolchain_version_tokens
     };
 
     let schema =
diff --git a/packages/fuel-indexer-tests/indexers/simple-wasm/simple_wasm.wasm b/packages/fuel-indexer-tests/indexers/simple-wasm/simple_wasm.wasm
index e69de29bb..2437b471e 100644
Binary files a/packages/fuel-indexer-tests/indexers/simple-wasm/simple_wasm.wasm and b/packages/fuel-indexer-tests/indexers/simple-wasm/simple_wasm.wasm differ
diff --git a/packages/fuel-indexer-tests/tests/snapshots/integration_tests__commands__default_indexer_config.snap b/packages/fuel-indexer-tests/tests/snapshots/integration_tests__commands__default_indexer_config.snap
index 83519cde3..59a847f27 100644
--- a/packages/fuel-indexer-tests/tests/snapshots/integration_tests__commands__default_indexer_config.snap
+++ b/packages/fuel-indexer-tests/tests/snapshots/integration_tests__commands__default_indexer_config.snap
@@ -40,4 +40,5 @@ replace_indexer: false
 accept_sql_queries: false
 block_page_size: 20
 allow_non_sequential_blocks: false
+disable_toolchain_version_check: false
 
diff --git a/packages/fuel-indexer-tests/tests/snapshots/integration_tests__commands__forc_index_start_help_output.snap b/packages/fuel-indexer-tests/tests/snapshots/integration_tests__commands__forc_index_start_help_output.snap
index da18a60e1..723751ee6 100644
--- a/packages/fuel-indexer-tests/tests/snapshots/integration_tests__commands__forc_index_start_help_output.snap
+++ b/packages/fuel-indexer-tests/tests/snapshots/integration_tests__commands__forc_index_start_help_output.snap
@@ -29,6 +29,10 @@ OPTIONS:
         --database <DATABASE>
             Database type. [default: postgres] [possible values: postgres]
 
+        --disable-toolchain-version-check
+            By default, Fuel Indexer will only accept WASM indexer modules compiled with the same
+            toolchain version as the version of Fuel Indexer.
+
         --embedded-database
             Automatically create and start database using provided options or defaults.
 
diff --git a/packages/fuel-indexer-tests/tests/snapshots/integration_tests__commands__fuel_indexer_api_server_run_help_output.snap b/packages/fuel-indexer-tests/tests/snapshots/integration_tests__commands__fuel_indexer_api_server_run_help_output.snap
index 1564a42e7..9b32e3ef2 100644
--- a/packages/fuel-indexer-tests/tests/snapshots/integration_tests__commands__fuel_indexer_api_server_run_help_output.snap
+++ b/packages/fuel-indexer-tests/tests/snapshots/integration_tests__commands__fuel_indexer_api_server_run_help_output.snap
@@ -23,6 +23,10 @@ OPTIONS:
         --database <DATABASE>
             Database type. [default: postgres] [possible values: postgres]
 
+        --disable-toolchain-version-check
+            By default, Fuel Indexer will only accept WASM indexer modules compiled with the same
+            toolchain version as the version of Fuel Indexer.
+
         --fuel-node-host <FUEL_NODE_HOST>
             Host of the running Fuel node. [default: localhost]
 
diff --git a/packages/fuel-indexer-tests/tests/snapshots/integration_tests__commands__fuel_indexer_run_help_output.snap b/packages/fuel-indexer-tests/tests/snapshots/integration_tests__commands__fuel_indexer_run_help_output.snap
index 80255a0ec..f7f9ca6c8 100644
--- a/packages/fuel-indexer-tests/tests/snapshots/integration_tests__commands__fuel_indexer_run_help_output.snap
+++ b/packages/fuel-indexer-tests/tests/snapshots/integration_tests__commands__fuel_indexer_run_help_output.snap
@@ -29,6 +29,10 @@ OPTIONS:
         --database <DATABASE>
             Database type. [default: postgres] [possible values: postgres]
 
+        --disable-toolchain-version-check
+            By default, Fuel Indexer will only accept WASM indexer modules compiled with the same
+            toolchain version as the version of Fuel Indexer.
+
         --embedded-database
             Automatically create and start database using provided options or defaults.
 
diff --git a/plugins/forc-index/src/ops/forc_index_start.rs b/plugins/forc-index/src/ops/forc_index_start.rs
index a94371b92..92c458a22 100644
--- a/plugins/forc-index/src/ops/forc_index_start.rs
+++ b/plugins/forc-index/src/ops/forc_index_start.rs
@@ -40,6 +40,7 @@ pub async fn init(command: StartCommand) -> anyhow::Result<()> {
         accept_sql_queries,
         block_page_size,
         allow_non_sequential_blocks,
+        disable_toolchain_version_check,
     } = command;
 
     let mut cmd = Command::new("fuel-indexer");
@@ -93,6 +94,10 @@ pub async fn init(command: StartCommand) -> anyhow::Result<()> {
             ("--verbose", verbose),
             ("--local-fuel-node", local_fuel_node),
             ("--allow-non-sequential-blocks", allow_non_sequential_blocks),
+            (
+                "--disable-toolchain-version-check",
+                disable_toolchain_version_check,
+            ),
         ];
         for (opt, value) in options.iter() {
             if *value {